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Thomas J Herzog Selected Research

liposomal doxorubicin (Doxil)

11/2021Phase 1b study of AVB-500 in combination with paclitaxel or pegylated liposomal doxorubicin platinum-resistant recurrent ovarian cancer.
1/2021Cardiac safety of trabectedin monotherapy or in combination with pegylated liposomal doxorubicin in patients with sarcomas and ovarian cancer.
6/2020Data on prior pegylated liposomal doxorubicin (PLD) treatment in recurrent ovarian cancer: Post-hoc data analysis from the phase 3 randomized, open-label study comparing trabectedin and PLD versus PLD alone in patients with recurrent ovarian cancer.
1/2020A phase 3 randomized, open-label, multicenter trial for safety and efficacy of combined trabectedin and pegylated liposomal doxorubicin therapy for recurrent ovarian cancer.
2/2017The efficacy of trabectedin in treating ovarian cancer.
11/2016Adverse Event Profile by Folate Receptor Status for Vintafolide and Pegylated Liposomal Doxorubicin in Combination, Versus Pegylated Liposomal Doxorubicin Alone, in Platinum-Resistant Ovarian Cancer: Exploratory Analysis of the Phase II PRECEDENT Trial.
10/2012Patient-reported outcomes in relapsed ovarian cancer: results from a randomized Phase III study of trabectedin with pegylated liposomal doxorubicin (PLD) versus PLD alone.
10/2012Trabectedin plus pegylated liposomal doxorubicin (PLD) versus PLD in recurrent ovarian cancer: overall survival analysis.
7/2010Trabectedin plus pegylated liposomal Doxorubicin in recurrent ovarian cancer.
1/2007Early changes in CA125 after treatment with pegylated liposomal doxorubicin or topotecan do not always reflect best response in recurrent ovarian cancer patients.
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Thomas J Herzog Research Topics

Disease

76Ovarian Neoplasms (Ovarian Cancer)
05/2022 - 01/2002
60Neoplasms (Cancer)
01/2022 - 03/2002
23Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2022 - 06/2003
18Endometrial Neoplasms (Endometrial Cancer)
09/2015 - 06/2002
15Carcinoma (Carcinomatosis)
10/2019 - 01/2002
12Ovarian Epithelial Carcinoma
01/2020 - 01/2004
6Neutropenia
02/2017 - 01/2002
6Ascites
06/2015 - 01/2002
5Neoplasm Metastasis (Metastasis)
04/2017 - 03/2004
5Hypertension (High Blood Pressure)
01/2017 - 11/2004
4Sarcoma (Soft Tissue Sarcoma)
01/2021 - 12/2004
4Disease Progression
01/2020 - 09/2003
4Fatigue
02/2017 - 10/2014
4Thrombocytopenia (Thrombopenia)
10/2014 - 01/2002
4Lymphatic Metastasis
12/2004 - 06/2003
3Infections
01/2017 - 11/2004
3Febrile Neutropenia
01/2017 - 01/2004
3Hemorrhage
07/2014 - 08/2013
3Wounds and Injuries (Trauma)
10/2013 - 06/2010
3Venous Thromboembolism
11/2011 - 06/2010
2Fallopian Tube Neoplasms
12/2021 - 01/2017
2Fever (Fevers)
01/2021 - 11/2014
2Endodermal Sinus Tumor (Endodermal Sinus Tumors)
07/2020 - 11/2004
2Uterine Neoplasms (Uterine Cancer)
01/2020 - 07/2013
2COVID-19
01/2020 - 01/2020
2Leiomyosarcoma
12/2018 - 11/2008
2Nausea
02/2017 - 11/2014
2Vomiting
02/2017 - 11/2014
2Proteinuria
01/2017 - 07/2014
2Endometriosis
01/2016 - 08/2013
2Abdominal Pain (Pain, Abdominal)
11/2014 - 07/2014
2Female Genital Diseases
05/2014 - 02/2013
2Pelvic Organ Prolapse
08/2013 - 11/2012
2Vulvar Neoplasms (Vulvar Cancer)
07/2013 - 09/2008
2Adenocarcinoma
01/2012 - 12/2007
2Clear Cell Adenocarcinoma
01/2009 - 12/2004
2Carcinosarcoma
11/2008 - 07/2008
2Hemolytic-Uremic Syndrome
04/2005 - 11/2004
2Anemia
11/2004 - 01/2002
1Microsatellite Instability
01/2020
1Osteosarcoma (Osteogenic Sarcoma)
01/2019
1Starvation
01/2019

Drug/Important Bio-Agent (IBA)

26PlatinumIBA
05/2022 - 01/2002
16liposomal doxorubicin (Doxil)FDA Link
11/2021 - 01/2002
14Paclitaxel (Taxol)FDA LinkGeneric
11/2021 - 01/2002
12Biomarkers (Surrogate Marker)IBA
12/2021 - 06/2010
11Topotecan (Hycamtin)FDA LinkGeneric
03/2011 - 01/2002
101-dodecylpyridoxal (PLD)IBA
11/2021 - 04/2005
10Carboplatin (JM8)FDA LinkGeneric
12/2020 - 01/2004
8Pharmaceutical PreparationsIBA
11/2021 - 07/2005
7TrabectedinIBA
01/2021 - 07/2010
7Proteins (Proteins, Gene)FDA Link
01/2019 - 01/2004
6Bevacizumab (Avastin)FDA Link
05/2022 - 11/2010
6taxaneIBA
01/2017 - 08/2006
4Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2022 - 01/2019
4Hormones (Hormone)IBA
01/2020 - 06/2010
4Cisplatin (Platino)FDA LinkGeneric
01/2019 - 07/2004
4GemcitabineFDA Link
03/2010 - 01/2004
4VaccinesIBA
05/2008 - 09/2003
4Deoxyglucose (2 Deoxy D glucose)IBA
12/2005 - 06/2003
3FANG vaccineIBA
12/2021 - 12/2020
3Docetaxel (Taxotere)FDA Link
03/2014 - 08/2003
3Topoisomerase I InhibitorsIBA
05/2008 - 01/2002
3DNA (Deoxyribonucleic Acid)IBA
12/2007 - 06/2002
2Monoclonal AntibodiesIBA
12/2021 - 01/2016
2AntigensIBA
04/2017 - 07/2016
2Folic Acid (Vitamin M)FDA LinkGeneric
11/2016 - 01/2016
2pazopanibFDA Link
03/2016 - 10/2014
2Progestins (Progestagens)IBA
09/2015 - 01/2004
2Phosphotransferases (Kinase)IBA
07/2013 - 02/2013
2Etoposide (VP 16)FDA LinkGeneric
11/2004 - 11/2004
1Poly Adenosine Diphosphate RiboseIBA
05/2022
1Immune Checkpoint InhibitorsIBA
12/2021
1NivolumabIBA
12/2021
1rucaparibIBA
12/2021
1EpitopesIBA
12/2021
1Death Domain ReceptorsIBA
12/2021
1Alkylating AgentsIBA
01/2021
1Chloroquine (Aralen)FDA LinkGeneric
01/2019

Therapy/Procedure

49Therapeutics
05/2022 - 01/2002
30Drug Therapy (Chemotherapy)
01/2022 - 01/2002
28Hysterectomy
10/2021 - 08/2004
9Radiotherapy
08/2014 - 09/2003
8Lymph Node Excision (Lymph Node Dissection)
01/2013 - 04/2002
5Immunotherapy
01/2022 - 01/2019
4Ovariectomy (Oophorectomy)
10/2021 - 04/2002
4Laparotomy
11/2004 - 03/2004
3Cytoreduction Surgical Procedures
12/2021 - 12/2011
3Adjuvant Chemotherapy
01/2019 - 10/2018
3Brachytherapy
08/2014 - 12/2011
3Neoadjuvant Therapy
04/2014 - 09/2008
3Adjuvant Radiotherapy
04/2009 - 10/2003
2Precision Medicine
01/2022 - 06/2012
2Length of Stay
06/2010 - 09/2003
2Aftercare (After-Treatment)
01/2007 - 11/2004
2Catheters
05/2006 - 01/2002
1Tubal Sterilization (Tubal Ligation)
10/2021
1Salpingectomy
10/2021
1Intravenous Infusions
01/2020
1Treatment Delay
10/2018